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目的比较新疆维吾尔族和汉族胃癌患者的血清肿瘤标志物的表达水平,并探讨其临床意义。方法观察对象来自我院肿瘤科收治的30例胃癌患者,以同期30例健康体检者作为健康组,用化学发光法检测两组患者血清癌胚抗原(CEA)、血清肿瘤相关糖类抗原(CA199、CA724)表达水平。结果肺癌组各分期的CEA、CA199、CA724水平均高于健康组(P<0.05);健康组中,汉族和维族的CEA、CA199、CA724水平比较差异不明显(P>0.05);胃癌组中,汉族胃癌Ⅰ期患者与维族胃癌Ⅰ期患者的CEA水平存在差异(P<0.05),而两组在Ⅱ和Ⅲ期患者的CA199、CA724水平无差异(P>0.05)。结论胃癌患者血清肿瘤标志物中,汉族和新疆维吾尔族的CA199级CA724水平无差异,CEA在Ⅰ期表达中具有明显差异。
Objective To compare the expression of serum tumor markers in gastric cancer patients with Uygur and Han nationality in Xinjiang and to explore its clinical significance. Methods The observational objects were from 30 patients with gastric cancer admitted to the Department of Oncology in our hospital. In the same period, 30 healthy persons were used as the healthy group. Serum CEA and serum tumor-associated carbohydrate antigens (CA199) were detected by chemiluminescence. , CA724) Expression level. Results The levels of CEA, CA199, CA724 in lung cancer group were higher than those in healthy group (P<0.05). In healthy group, the levels of CEA, CA199, and CA724 in Han and Uighur were not significantly different (P>0.05); There was a significant difference in CEA levels between patients with stage I gastric cancer and stage I patients with Uighur gastric cancer (P<0.05). There was no difference in CA199 and CA724 levels between stage II and stage III patients (P>0.05). Conclusion There are no differences in serum CA199 levels between Han and Xinjiang Uighurs in serum tumor markers of gastric cancer patients. There is a significant difference in CEA expression in stage I.