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目的:观察不能手术切除的中晚期原发性巨块型肝癌应用健脾化瘀合剂加全肝移动条放射治疗的临床疗效。方法:将40例患者随机分为两组,治疗组20例应用健脾化瘀合剂加全肝移动条放射治疗,并与单纯西药保肝对症治疗20例作对照观察。结果:(1)治疗组与对照组近期疗效总缓解率分别为65%和40%(P>0.05);(2)临床证候变化比较:治疗组与对照组总改善率分别为75%和45%(P<0.05)。(3)生活质量变化比较:治疗组与对照组提高稳定率分别为80%、50%。两组患者半年、一年生存率分别为65%、35%和40%、20%,中位生存期平均为6.2个月、3.8个月(P<0.05)。结论:对于不能手术切除的中晚期原发性巨块型肝癌患者应用健脾化瘀合剂加全肝移动条放射治疗可改善巨块型肝癌患者的临床症状,有效地控制病情及延缓病情发展,并能缓解疼痛,提高生活质量,延长生存期。
Objective: To observe the clinical effect of Jianpi Huayu Mixture plus whole liver moving strip radiotherapy in the treatment of unresectable primary massive liver cancer. Methods: Forty patients were randomly divided into two groups. 20 cases in the treatment group were treated with Jianpi Huayu Mixture plus whole liver moving strip radiotherapy and compared with the simple western medicine liver protection symptomatic treatment in 20 cases. Results: (1) The total effective rates of the treatment group and the control group were 65% and 40% respectively (P> 0.05); (2) Comparison of clinical syndromes: The total improvement rates of the treatment group and the control group were 75% 45% (P <0.05). (3) The quality of life comparison: The treatment group and the control group increased the stability rate respectively 80%, 50%. The half-year and one-year survival rates were 65%, 35% and 40%, respectively. The median survival time was 6.2 months and 3.8 months (P <0.05). Conclusion: The application of “Jianpi Huayu Mixture plus whole liver moving strip radiotherapy” can improve the clinical symptoms of patients with massive liver cancer and effectively control the condition and delay the progression of the disease in patients with advanced primary massive liver cancer who can not be surgically removed. And can relieve pain, improve quality of life and prolong survival.