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结扎胰导管是造成胰腺机能障碍的实验方法之一。在结扎胰导管的早期,血中胰酶的含量,特别是淀粉酶和脂肪酶呈现明显的升高。Adlersberg观察到,在动物的实验性胰腺炎的早期与血清淀粉酶升高的同时,还伴有血中总脂水平的升高。Dreiling等发现,对正常人及糖尿病人应用影响血糖水平的药物和激素时,血浆淀粉酶和自由脂肪酸表现明显的平行性变化:例如,胰岛素或葡萄糖可使二者同时下降;而肾上腺素则使二者同时升高。
Ligation of the pancreatic duct is one of the experimental methods of pancreatic dysfunction. Early in the ligation of the pancreatic duct, trypsin levels in the blood, especially amylase and lipase showed a significant increase. Adlersberg observed that in the early stages of experimental pancreatitis in animals, elevated serum amylase was accompanied by an increase in total lipid levels in the blood. Dreiling et al. Found that plasma amylase and free fatty acid showed significant parallel changes in both normal and diabetic patients when using drugs and hormones that affect blood sugar levels: for example, insulin or glucose both decreased at the same time; and epinephrine Both rise at the same time.