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微型胶囊(简称微囊Microcapsules)用复凝聚方法制备时,是用两种荷相反电荷的囊材(包囊材料),在一定pH值下,正、负电荷的变化引起相分离而凝聚形成微囊的。其关键是选择一定pH值时两种囊材所荷的正、负电荷量相等时配比浓度。此浓度比例下,凝聚最完全,为二者的最佳配比量。在Zeta电位测定仪上则表现为两者的电泳速度相等。否则两种囊材比例不当,则凝聚不完全,成囊率低、囊壁厚薄不均、稳定性差等。本文应用Zeta电位测定仪,筛选出了用明胶分别与阿拉伯胶、桃胶、海藻酸、羧甲基纤维素(CMC),邻苯二甲酸醋酸纤维素(CAP)制备微囊时的最佳配比量以及此比例下的成囊结果。此法从微囊形成的理论出发,运用微观电泳的方法、直观、准确地测定了囊材配比的新方法。对微囊生产具有重要意义。
Microcapsules (microcapsules for short) are prepared by the complex coacervation method using two oppositely charged capsular materials (encapsulating materials). Under certain pH, the change of positive and negative charges causes phase separation and condensation to form micro Bag The key is to select a certain pH value of the two capsule material when the positive and negative charge is equal when the concentration ratio. This concentration ratio, the most complete aggregation, the best ratio between the two. The Zeta Potentiometer shows an equal rate of electrophoresis between the two. Otherwise, the two kinds of material ratio of the bladder is not properly, then the aggregation is not complete, the rate of encapsulation is low, uneven wall thickness, poor stability and so on. In this paper, Zeta potential analyzer was used to screen out the best preparation of microcapsules with gelatin and acacia, peach gum, alginate, carboxymethyl cellulose (CMC), cellulose acetate phthalate (CAP) Volume and results of the encapsulation at this ratio. Based on the theory of microcapsule formation, this method uses the method of microscopic electrophoresis to determine the new method of capsule material ratio intuitively and accurately. Microcapsule production is of great significance.