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电刺激家兔一侧主动脉神经（ＡＮ）引起心动过缓和降压反应。在同侧孤束核（ＮＴＳ） 内注射γ氨基丁酸（ＧＡＢＡ） 或吗啡，能基本阻断这种诱发的心动过缓和降压反应，但不影响基础血压和基础心率。ＮＴＳ内注射ＧＡＢＡ受体拮抗剂荷苞牡丹碱可拮抗吗啡的上述作用，但吗啡受体拮抗剂纳络酮几乎不影响ＧＡＢＡ对诱发压力感受性反射的阻断效应。结果提示：孤束核内ＧＡＢＡ和阿片肽系统对诱发压力感受性反射有抑制作用，吗啡可能通过ＧＡＢＡ受体激活而发挥作用。
Electrical stimulation of the rabbit aortic nerve (AN) causes bradycardia and hypotensive responses. Injection of gamma aminobutyric acid (GABA) or morphine in the ipsilateral nucleus tractus solitarius (NTS) substantially blocked this induced bradycardia and hypotensive response, but did not affect basal blood pressure and basal heart rate. NTS injection of GABA receptor antagonist chesnut could antagonize the above effects of morphine, but the morphine receptor antagonist naloxone almost did not affect the blockade effect of GABA on the induction of baroreflex. The results suggest that GABA and opioid system in nucleus tractus solitarius can inhibit the induction of baroreflex and morphine may play a role in the activation of GA-BA receptor.