Synthesis, Crystal Structure and Biological Activity of N-tert-butyl-N-(4-methyl-1,2,3-thiadiazole)-

来源 :结构化学 | 被引量 : 0次 | 上传用户:sunyanzi168168168
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
The title compound N-tert-butyl-N-(4-methyl-1,2,3-thiadiazole)-5-yl-N-(4-me-thyl1,2,3-thiadiazole)-5-formyl-N-3,5-dichloropyrid-2-yl-diacylhydrazines (C18H17C12N7O3S2, Mr=514.41) has been synthesized by the reaction of N-tert-butyl-N-3,6-dichloropyridine-2-formyl hydrazine with 4-methyl-1,2,3- thiadiazole-5-carbonyl chloride and triethylamine, and its structure was characterized by 1H NMR, HR MS, and single-crystal X-ray diffraction. The crystal of the title compound belongs to monoclinic, space group C2/c with a = 27.726(8), b = 11.045(3), c = 14.507(4)(A), β = 96.758(4)°, Z = 8, V= 4412(2) (A)3, Dc = 1.549 g/cm3, μ = 0.521 mm-1, F(000) = 2112, R =0.0405 and wR = 0.1153. X-ray analysis indicates that all rings are non-planar in this molecule. The bioassay results indicate that both the title compound and the positive control RH-5992 have weak fungicide activities, while the title compound has good insecticidal activity against Plutella xylostella L. and no insecticidal activity against Culex pipiens pallens. su
其他文献
蛋白质组学是一门研究蛋白质结构和功能的科学,双向凝胶电泳技术和质谱技术是蛋白质组学的核心技术,蛋白质组学技术的快速发展和广泛应用明显加快了人类感染性疾病发病机制的
NaA zeolite with average particle size of 1 μm was successfully synthesized by microwave heating. Influences of pre-crystallization time, microwave power and m
心力衰竭(心衰)是一种复杂的临床症状群,是各种心血管疾病发展的最后阶段.据2003年调查资料,我国35~74岁成年人中约有400万心衰患者,心衰已成为我国心血管病领域的重要公共卫
In this study, a simple and rapid high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method was established and validated to determine
本文概述了目前电子电器行业面临的对于有害化学物质限制要求的发展状况,即后RoHS时代的形势概况.同时以新的视角,观念和方法推荐了WBS系统概念,推荐给企业一个崭新的方法,告
We consider the energy saving problem for caches on a multi-core processor. In the previous research on low power processors, there are various methods to reduc
为了研究兖州煤田综采薄煤层底板采动变形破坏规律,应用现场应变实测系统在兖矿集团杨村煤矿4602综采工作面进行了现场实测,得到了底板2个监测钻孔8个应变传感器探头的的应变
The modern near-infrared(NIR) spectroscopy analysis is a simple, efficient and nondestructive technique, which has been used in chemical analysis in diverse fie
Currently, global-features-based image copy detection is vulnerable to geometric transformations like cropping, shift, and rotations. To resolve this problem, s
By analyzing the data of longitudinal speed, transverse speed and rudder angle etc. in the simulated 10°/10° zigzag test, the hydrodynamic derivatives in the