论文部分内容阅读
目的评价中西医结合优化方案治疗登革热的临床疗效。方法开展前瞻性随机对照研究,共入组登革热病例160例,采用随机数字表将患者分为对照组和治疗组,每组各80例。对照组予以西医常规治疗,治疗组在此基础上联合中医辨证论治口服中药治疗。观察两组的临床疗效。结果两组患者治疗后比较,平均热退时间、住院时间、病程、白细胞和血小板恢复时间、中医症状体征评分等方面差异有统计学意义(P<0.05);安全性指标比较,所有患者在治疗期间均未出现与中药相关的不良反应。患者中约有一半患者出现肝功能异常(88例),仅次于血液系统损害,两组患者治疗后肝功能比较,组间比较无显著统计学差异(P>0.05);同组患者治疗前后肝功能比较无统计学差异(P>0.05)。结论中西医结合治疗登革热的临床疗效优于单纯西医治疗,能改善临床症状,安全性高,但改善肝功能方面尚需进一步研究。
Objective To evaluate the clinical efficacy of optimized combination of traditional Chinese and western medicine in the treatment of dengue fever. Methods A prospective randomized controlled study was conducted in 160 patients with dengue fever. The patients were divided into control group and treatment group with random number table, 80 cases in each group. The control group was given routine treatment of Western medicine, and the treatment group was treated with traditional Chinese medicine based on TCM syndrome differentiation. The clinical efficacy of the two groups was observed. Results After treatment, the average reheat time, length of hospital stay, duration of disease, recovery time of leukocytes and platelets, symptom and symptom score of TCM were significantly different between the two groups (P <0.05). Compared with the safety index, During the period did not appear with traditional Chinese medicine-related adverse reactions. About half of the patients had abnormal liver function (88 cases), second only to the blood system damage. There was no significant difference between the two groups in the liver function after treatment (P> 0.05) There was no significant difference in liver function (P> 0.05). Conclusion The clinical efficacy of integrated traditional Chinese and western medicine in the treatment of dengue fever is better than that of western medicine alone. It can improve clinical symptoms and safety, but further study is needed in improving liver function.