肾缺血再灌注损伤(Ischemiarepe rfusion injury,IRI)是指肾组织缺血时和其后恢复血液灌注时器官功能不能恢复正常,甚至发生更为严重的组织损伤或器官功能衰竭。肾脏由于其组织结构和功能的特殊性,是对缺血再灌注损伤敏感的器官之一。在临床上常见于失血或中毒性休克、弥散性血管内凝血、肾移植、肾部分切除、肾实质 Ischemiarepe rfusion injury (IRI) refers to the organ function can not be restored to normal even when the renal tissue is reperfused, and even more serious tissue damage or organ failure occurs during the reperfusion of the renal tissue. Due to the particularity of its structure and function, the kidneys are one of the organs that are sensitive to ischemia-reperfusion injury. Common in clinical blood loss or toxic shock, disseminated intravascular coagulation, kidney transplantation, partial nephrectomy, renal parenchyma