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过去已在胸腺中分离到几种激素样因子,胸腺素α_1(Tα_1)为其中的一种,它位于胸腺上皮细胞。美国Naz 等首次报告人类精浆和卵泡液中存在高浓度 Tα_1。19名男性精浆中 Tα_1浓度变异范围为614-2604pg/ml(均值±SD 约为1682±454 pg/ml)。Tα_1浓度与射出精液中精子总数和精液体积间都显示相关。不育男性 Tα_1浓度低,精子数目少,精子运动减少,精浆体积小。取自10名不育女性24个卵泡的卵泡液中,Tα_1浓度变异范围为1019至6384pg/ml(均值±SD
In the past, several hormone-like factors have been isolated in the thymus. Thymosin alpha 1 (Tα_1) is one of them and is located in the thymus epithelium. For the first time in the United States, Naz et al reported that there was a high concentration of Tα_1 in 19 seminal plasma of human seminal plasma and follicular fluid. The range of Tα 1 concentration ranged from 614 to 2604 pg / ml (mean SD ± 1682 ± 454 pg / ml). The concentration of Tα_1 is correlated with the total number of sperm and semen volume in the ejaculated semen. Male infertility Tα_1 low concentration, sperm count less, sperm motility decreased, seminal vesicle size is small. In the follicular fluid from 24 follicles from 10 infertile women, the Tα_1 concentration ranged from 1019 to 6384 pg / ml (mean ± SD