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目的:了解广西侗族人群ABO及Rh血型分布及基因频率。方法:对检测人群严格入选标准,随机抽取1927例非血缘关系的广西侗族人群进行ABO及Rh血型鉴定和分析。结果:ABO血型分布特征:O>B>A>AB;基因频率p(A)=0.1556、q(B)=0.1920、r(O)=0.6524;Rh(D)阴性率为0.052%,d基因频率0.0228。Rh发现8种表型,以CCDee频率最高(65.28%),未发现CCDEE表型。组合体基因频率以CDe(0.8080)为最高。结论:广西侗族人群ABO、Rh血型分布符合国内南方少数民族的分布特征,但Rh阴性比例明显低于汉族人群。
Objective: To understand the distribution and gene frequency of ABO and Rh in Guangxi Dong population. Methods: According to the strict selection criteria of the population, 1927 non-blood-related Guangxi Dongs were randomly selected for ABO and Rh blood type identification and analysis. Results: The distribution of ABO blood type was: O> B> A> AB. The frequency of gene (p = 0.1556, q = 0.1920, r Frequency 0.0228. Rh found eight phenotypes, the highest CCDee frequency (65.28%), did not find the CCDEE phenotype. The frequency of the combinatorial genes was highest at CDe (0.8080). Conclusion: The distribution of ABO and Rh blood groups in Dongs in Guangxi is in line with the distribution characteristics of ethnic minorities in southern China, but the proportion of Rh negatives is significantly lower than that of Han nationality.