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目的:研究苦碟子对恶性肿瘤化疗后并发下肢深静脉血栓的临床防治效果。方法:选取2012年10月—2014年10月肿瘤科收治的70例恶性肿瘤患者为研究对象,采用对照研究的方式将其分为研究组和对照组,每组35例,对照组行单纯化疗治疗,研究组在化疗前后配合苦碟子注射液静续滴治疗,疗程结束后分析比较疗效及并发症发生率。结果:研究组患者治疗总有效率为91.43%,对照组为85.71%;两组患者治疗后下肢深静脉血栓发生率以及总不良反应率比较χ2=14.806 5、7.988 8,生存质量评分比较t=13.279 2;均P<0.01,差异具有统计学意义。结论:恶性肿瘤患者在化疗前后配合苦碟子注射液治疗效果与单纯化疗相当,可明显改善患者生活质量,且不良反应发生率明显降低,有效降低下肢深静脉血栓发生率,具有广阔的临床使用前景。
Objective: To study the clinical effect of Kudiezi in the treatment of deep venous thrombosis of lower extremities after chemotherapy. Methods: Seventy patients with malignant tumors admitted to Department of Oncology from October 2012 to October 2014 were selected as study objects. The patients in study group were divided into study group and control group with 35 cases in each group. The control group received simple chemotherapy Treatment, the study group before and after chemotherapy with Kudie injection intravenous drip treatment, after the end of treatment analysis and comparison of efficacy and incidence of complications. Results: The total effective rate was 91.43% in the study group and 85.71% in the control group. The incidence of deep venous thrombosis and the total adverse reaction rate in the two groups were χ2 = 14.806 5,7.9888 after treatment. The quality of life score was t = 13.279 2; all P <0.01, the difference was statistically significant. Conclusion: The treatment of malignant tumor patients with Kudiezi injection before and after chemotherapy is equivalent to chemotherapy alone, which can significantly improve the quality of life of patients and significantly reduce the incidence of adverse reactions, and effectively reduce the incidence of deep venous thrombosis of the lower extremities, and has broad clinical application prospects .