血管内皮祖细胞(endothelial progenitor cells,EPC)是血管内皮细胞的前体细胞,主要来源于骨髓、脐血、成人外周血,不仅参与胚胎血管形成,而且在出生后的血管生成过程中有重要的促进作用。妊娠是对母体血液循环系统的巨大挑战,需要机体系统性地适应和子宫发生足够变化。子痫前期患者及妊娠期糖尿病患者中多存在内皮功能的失衡。就近年对妊娠中EPC的研究进展综述。 Endothelial progenitor cells (EPCs), the precursors of vascular endothelial cells, are mainly derived from bone marrow, cord blood and adult peripheral blood. They are not only involved in embryonic vascularization but also important in angiogenesis after birth enhancement. Pregnancy is a tremendous challenge to the maternal blood circulation system, requiring the body to adapt systematically and enough to change the uterus. There are many imbalances of endothelial function in patients with preeclampsia and gestational diabetes mellitus. Recent Research Progress on EPC in Pregnancy.