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目的了解女性不孕不育患者支原体感染状况以及解脲支原体(UU)和人型支原体(MH)对抗生素的敏感情况,以指导临床合理用药,减少耐药菌株的产生。方法收集2009年1月～2010年1月期间在我院就诊的120例不孕不育女性作为观察组。选择同期在我院进行健康体检的育龄女性120例作为对照组。两组均进行泌尿生殖道标本支原体培养及药敏试验。结果观察组的UU,MH和UU+MH感染率均显著高于对照组(P<0.05);观察组感染的支原体对喹诺酮类和大环内酯类抗生素耐药率较高,对强力霉素、美满霉素、交沙霉素耐药较低。结论不孕不育女性生殖道支原体感染率较高;药敏试验结果有助于指导临床医生合理用药。
Objective To understand the prevalence of mycoplasma infection and the susceptibility of UU and MH to antibiotics in female infertility patients so as to guide clinical rational drug use and reduce the production of drug-resistant strains. Methods A total of 120 infertile women in our hospital from January 2009 to January 2010 were recruited as the observation group. Select the same period in our hospital for physical examination of 120 women of reproductive age as a control group. Both groups were genitourinary tract mycoplasma culture and drug sensitivity test. Results The infection rates of UU, MH and UU + MH in the observation group were significantly higher than those in the control group (P <0.05). Mycoplasma infection in the observation group had a higher resistance rate to quinolones and macrolide antibiotics, , Minocycline, josamycin resistance lower. Conclusion Infertility female genital mycoplasma infection rate is high; drug susceptibility test results help to guide clinicians rational drug use.