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目的 探讨急性白血病免疫表型特点及临床意义。方法 应用间接免疫荧光法对 71例初治急性白血病进行膜免疫表型的检测。结果 急性非淋巴细胞白血病 (ANLL) 5 5例中 ,My+ ANLL ,CD+ 15ANLL、My-ANLL分别占 83 .6%、76.4%、16.4% ,完全缓解 (CR)率分别为 67.3 %、73 .8%、2 5 .0 % ,My+ ANLLCR率高于My-ANLLCR率 (P <0 .0 1) ;16例ALL中 ,8例单系ALLCR率 75 .0 % ,5例兼表达髓系抗原及淋系抗原ALLCR率 2 0 .0 % ,2例裸型ALL未缓解 ,1例DR+ 型ALLCR。结论 CD15在ANLL中检出率高 ,是较好的辅助诊断指标。My+ ANLL预后较好。
Objective To investigate the immunophenotype and clinical significance of acute leukemia. Methods Indirect immunofluorescence was used to detect membrane immunophenotype in 71 cases of newly diagnosed acute leukemia. Results Of the 55 non-acute lymphocytic leukemia (ANLL) patients, My+ ANLL, CD+15ANLL, and My-ANLL accounted for 83.6%, 76.4%, and 16.4%, respectively. Complete remission (CR) rates were 67.3% and 73.8, respectively. %, 25.0%, My+ANLLCR rate was higher than My-ANLLCR rate (P < 0.01); in 8 cases of ALL, 8 cases had a single system ALLCR rate of 75.0 %, 5 cases also expressed myeloid antigen and The ALLCR rate of lymphoid lineage antigen was 20%, 2 cases of nude ALL did not relieve, and 1 case of DR+ type ALLCR. Conclusion The detection rate of CD15 in ANLL is high and it is a good auxiliary diagnostic indicator. My+ ANLL has a good prognosis.