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目的:获取我省国人消化性溃疡的流行病学特征资料。方法:采用同时性、前瞻性调查,自1997年1月至1997年12月止收集新确诊的溃疡病例,记录性别、年龄、职业、溃疡病灶的部位、大小、数量及是否合并HP感染等。结果:共调查11983例消化性溃疡患者,消化性溃疡的年发病率根据标准化人口统计估计为0.084%,男女患病比为3.6:1,从业人员中以管理人员发病率最高,达0.40%,高峰年龄组为30-49岁,十二指肠球部溃疡与胃溃疡的发病比为1.9:1,溃疡大小以<10mm居多,占80%以上,胃溃疡和十二指肠球部溃疡的好发部位分别是小弯和前壁。幽门螺旋杆菌(HP)感染阳性率为73.8%。结论:消化性溃疡是我省的一种多发疾病,其年发病率估计为0.084%,此病好发于壮年,男性居多,管理人员中发病率最高;我省男性多吸烟是导致男性溃疡多发的主要因素;HP阳性占消化性溃疡的比例数以前有明显下降。
Objective: To obtain the epidemiological characteristics of peptic ulcer in our province. Methods: Simultaneous and prospective investigations were conducted to collect newly diagnosed cases of ulcer from January 1997 to December 1997 and to record the location, size, quantity and age, occupational and ulcer lesions, and the presence or absence of HP infection. Results: A total of 11983 patients with peptic ulcer were investigated. The annual incidence of peptic ulcer was estimated to be 0.084% based on standardized demographic statistics. The prevalence ratio of male to female was 3.6: 1. The highest incidence of management staff was among the employees, Up to 0.40%. The peak age group was 30-49 years old. The incidence of duodenal ulcer and gastric ulcer was 1.9: 1. The ulcer size was mostly <10mm, accounting for more than 80%. The gastric ulcer and Duodenal ulcers are the lesser curvature and anterior wall, respectively. The positive rate of Helicobacter pylori (HP) infection was 73.8%. Conclusions: Peptic ulcer is a multi-disease in our province. The annual incidence rate is estimated to be 0.084%. The disease occurs predominantly in the prime of life, with the majority of males and the highest incidence among managers. In our province, male smoking is the most common cause of males The main factors of multiple ulcers; HP positive accounts for the proportion of peptic ulcer decreased significantly before.