论文部分内容阅读
目的 探讨创伤性休克患者血浆肾上腺髓质素 (AM)的变化特点及其机制。方法 选择 9例合并创伤性休克的多发伤患者作为研究对象 ,于休克早期 (EP)和晚期 (LP)分别用放免法测定血浆AM浓度。结果 EP和LP时血浆AM分别增加了 32 0 %和 170 % (P <0 0 5 )。结论 创伤性休克患者血浆AM在休克早、晚期均显著性升高 ,提示AM在创伤性休克发生发展中起重要的调节作用。
Objective To investigate the characteristics and mechanisms of plasma adrenomedullin (AM) in patients with traumatic shock. Methods Nine patients with multiple trauma with traumatic shock were enrolled in this study. Plasma AM concentration was measured by radioimmunoassay in the early and early stages of shock (LP). Results Plasma AM increased by 32 0% and 170%, respectively, at EP and LP (P <0 05). Conclusions AM in patients with traumatic shock increased significantly early and late shock, suggesting that AM plays an important role in the development of traumatic shock.