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顽固性高血压患者有较高的非杓型血压发生率,且与心血管事件的风险增加相关。非杓型血压部分与高血压患者清晨一次服药不能持续24h降压相关。方法:入选1794名顽固性高血压患者,根据服药时间分组(醒后服用所有降压药或睡前至少服用1种降压药),研究服药时间对其动态血压和临床特
Patients with refractory hypertension have a higher prevalence of non-dipper blood pressure and are associated with an increased risk of cardiovascular events. Non-dipper blood pressure and hypertension in patients with early morning medication can not be sustained 24h antihypertensive. Methods: A total of 1794 patients with refractory hypertension were enrolled in this study. Patients were divided into groups according to the time of taking medicine (taking all antihypertensive drugs after taking the medicine or taking at least one kind of antihypertensive drugs before going to bed) to study the effects of taking the medicine on ambulatory blood pressure and clinical features