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在诱导地鼠颊囊癌全过程中，采用墨汁灌注血管铸型技术、微循环形态和机能显微摄象测定技术，结合组织学检查，动态研究了颊囊癌变及肿瘤生长中的血管构筑过程和肿瘤区血流灌注量的变化情况。结果发现，血管生成现象不仅出现在肿瘤期，早在癌变前期就有明显表现，并随肿瘤生长而更加突出。肿瘤组织内的血流灌注量也随病变组织的癌变和肿瘤生长而增加，以满足肿瘤细胞分裂增殖所需的营养供给。但血流总量的增长幅度与血管生成并不一直成比例，到肿瘤生长中晚期，血流总量的涨幅低于血管密度涨幅，其原因认为同肿瘤所致的高粘血症有关。
In the process of inducing hamster cheek pouch carcinoma, blood vessel perfusion of vascular casts, microcirculation morphology and functional microscopic imaging techniques were combined with histological examination to dynamically study the vascular architecture during buccal cystic carcinogenesis and tumor growth. And the amount of blood flow in the tumor area. As a result, it was found that the angiogenesis phenomenon not only appeared in the tumor stage, but also became apparent in the early stages of canceration and became more prominent as the tumor grew. The amount of blood flow in the tumor tissue also increases with the cancerous tissue and tumor growth of the diseased tissue to meet the nutrient supply required for tumor cell proliferation and proliferation. However, the increase in total blood flow is not always proportional to angiogenesis. By the middle and late stages of tumor growth, the increase in total blood flow is lower than the increase in vascular density, which is thought to be related to hyperviscosity caused by tumors.