能够预测病人对某种药物的反应长期以来一直是临床医生的目标。分子生物学的快速发展使得研究人员相信一个个体的基因类型及其对药物的反应之间存在着某种联系。遗传药理学着重研究不同个体之间在药物代谢、药效和副反应方面出现差异的分子机制。现就临床常用的麻醉药和镇痛药的遗传药理学加以综述 Being able to predict a patient’s response to a drug has long been the goal of clinicians. The rapid advances in molecular biology have led researchers to believe there is a link between the genotype of an individual and its response to the drug. Pharmacogenetics focuses on the molecular mechanisms underlying the differences in drug metabolism, pharmacodynamics, and side effects among different individuals. The general pharmacology of anesthetics and analgesics are summarized