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目的 了解上海北蔡镇老年人群骨密度(Bone mineraldensity,BMD)变化规律及骨质疏松(Osteoporosis,OP)患病率,为本地区骨质疏松症的防治提供参考.方法 使用美国GE公司的Lunar Prodigy Advance PA+300164型双能X线骨密度仪对608例上海北蔡镇60～79岁老年人正位腰椎和左股骨近端进行骨密度测定,男性205例,女性403例.结果 随着年龄的增加髋部BMD逐渐下降,而腰部BMD不随年龄的增加而下降.男性组与女性组OP患病率差异有显著性(P<0.001);60～64、65～69、70～74、75～79岁组OP患病率差异有显著性(P<0.05).结论 上海北蔡镇老年人群OP患病率随年龄增高而增高,70～79岁女性骨质疏松的患病率最高,预防骨折的重点在老年妇女.老年人应坚持适当的体育活动,及时检查骨密度,积极治疗骨质疏松症,并注意防止跌倒导致的骨折发生.“,”Objective To investigate the prevalence rate of osteoporosis and the changes of BMD in the aged adults in Beicai town of Shanghai.Methods The investigation was conducted in 608 aged of 60-79 years old humans including 205 men and 403 women. Everyone was given BMD assay of lumbar spine and total hip by GE DEXA machine.Results The hip BMD decreased when the age increased, otherwise the lumbar BMD did not increase when the age increased. There were significant statistical differences among the group of 60-64y、65-69y、70-74y、75-79y(P<0.05). Moreover, the prevalence rate of osteoporosis in men was lower than women in each group (P<0.05).Conclusion The prevalence rate of osteoporosis in aged people of Beicai town increased with the age increased, the highest rate is of the group of age 70-79years old women. It can be concluded that the focus of fragility fracture prevention is on the aged women.