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脂联素(Adiponectin)是新近发现的脂肪组织特异分泌的一个具有重要功能的细胞因子。最近研究发现脂联素可能通过改善胰岛β细胞功能、抑制β细胞凋亡等机制抑制糖尿病的发生、发展。深入研究胰岛β细胞脂联素及脂联素受体的作用和调节机制,可为糖尿病的诊治提供新思路。
Adiponectin is a newly discovered cytokine secreted by adipose tissue that has an important function. Recent studies found that adiponectin may inhibit the occurrence and development of diabetes by improving the mechanism of pancreatic β-cell function and inhibiting β-cell apoptosis. In-depth study of pancreatic β-cell adiponectin and adiponectin receptor role and regulatory mechanisms for the diagnosis and treatment of diabetes provide new ideas.