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目的 探讨一氧化氮 (NO)及一氧化氮合酶 (NOS)在儿童癫患者中血清活性水平及意义。方法 采用化学比色法对12 4例儿童癫患者血清中NO及NOS活性水平进行检测。结果 儿童癫患者发作期及间歇期血清中NO及NOS活性水平均显著高于对照组 (P <0 0 1) ,发作期血清中NO及NOS活性水平均高于间歇期 (P <0 0 5 )。结论 NO及NOS在儿童癫病理过程中起重要作用
Objective To investigate the serum levels of nitric oxide (NO) and nitric oxide synthase (NOS) in children with epilepsy and their significance. Methods The serum levels of NO and NOS in 124 children with epilepsy were detected by chemical colorimetry. Results Serum levels of NO and NOS in children with epilepsy were significantly higher than those in the control group (P <0.01). The levels of NO and NOS in sera of children with epilepsy were significantly higher than those of patients with intermittent seizures 5). Conclusion NO and NOS play an important role in the pathological process of epilepsy in children