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249例消化性溃疡(PU),计十二指肠溃疡(DU)168例,胃溃疡(GU)81例。分别采用丽珠得乐(D组)及雷尼替丁胃舒平二药联用(RW组)门诊治疗4周后,愈合率在DU分别为79.3％及83％(P>0.25),在GU分别为68％及84.8％(P>0.05),均无显著性差异。疼痛消失率以及疼痛消失所需时间,无论在DU或GU,两治疗组均无明显差异。表明丽珠得乐在促进溃疡愈合及消除疼痛方面,无论对GU或DU均具有与雷尼替丁胃舒平二药联用相似的效果,而幽门螺旋菌(Hp)清除率在D组明显优于RW组。
There were 249 cases of peptic ulcer (PU), 168 cases of duodenal ulcer (DU) and 81 cases of gastric ulcer (GU). The rates of healing in the DU group were 79.3% and 83% (P> .25), respectively, when treated with L-pendimethalin (group D) and ranitidine (group RW) 68% and 84.8% (P> 0.05), no significant difference. The rate of pain disappearance and the time required for the pain to disappear did not differ between the two treatment groups, either in DU or GU. The results showed that in the promotion of ulcer healing and pain relief, both GU and DU have the same effect as the combined use of ranitidine and stomach Shu-ping, and H. pylori (Hp) clearance rate was significantly better than that of group D RW group.