自从五十年代初发现了流感病毒吸附到红细胞上需要细胞膜的唾液酸以来,人们对细胞表面糖基在细胞间相互识别中(如淋巴细胞“归巢”、肿瘤的侵润、滋养层细胞的植入、细胞间的粘连等)的作用有了日新月异的认识。与此同时,有关能特异地识别和结合特异糖基的凝集素的知识也日益增多,不 Since the discovery of the membrane-bound sialic acid required for the attachment of influenza virus to erythrocytes in the early 1950s, there has been a growing number of cell-surface glycosylation interactions among cells (eg, “homing” of lymphocytes, infiltration of tumors, Implantation, cell adhesion, etc.) have a rapid change of understanding. In the meantime, there is an increasing knowledge about agglutinins that specifically recognize and bind to specific glycosyl groups, and not