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日本血吸虫雄虫在4℃或37℃的HBS及无~(45)Ca~(2α)的HBS中经吡喹酮1或30μg/ml作用0.5～2h后,未见虫的Ca~(2+),Mg~(2+)含量有明显变化,但除4℃的HBS组外,余2组虫的K~+含量明显减少,而虫的Na~+含量的增加则不明显。在含30 mM Mg~(2+)的HBS中,雄虫经吡喹酮作用1h后,虫的Mg~(2+)含量明显增加。在37℃的HBS中,血吸虫雄虫经吡喹酮1μg/ml作用5～60min后,虫的皮层胞质中的~(45)Ca~(2α)含量的百分比较各相应对照组的明显减少,而虫体肌肉的则相反。在4℃的HBS或无~(45)Ca~(2α)的HBS中,吡喹酮对~(45)Ca~(2α)在虫体内的分布无明显影响。
After being treated with praziquantel 1 or 30 μg / ml for 0.5 ~ 2 h at 4 ℃ or 37 ℃ in HBS and without (45) Ca ~ (2α) HBS, ), And Mg 2+ content changed obviously. However, except the 4 ℃ HBS group, the contents of K + in the two groups of worms decreased significantly, but the increase of Na + in the insects was not obvious. In the HBS containing 30 mM Mg 2+, the content of Mg 2+ in the worm increased significantly after treated with praziquantel for 1 h. In the 37 ℃ HBS, the percentage of ~ (45) Ca ~ (2α) in the cytoplasm of the worm was significantly lower than that of the corresponding control group after being treated with praziquantel 1μg / ml for 5 ~ 60min , While the parasite muscle is the opposite. There was no significant effect of praziquantel on the distribution of ~ (45) Ca ~ (2α) in the worms at 4 ℃ in HBS or without ~ (45) Ca ~ (2α) HBS.