自从1984年以来,临床一直主要依赖PSA检查来筛选前列腺癌病人并借此随访治疗效果。由于前列腺癌的确诊依靠病理检查,因此,回顾研究发现,绝大多数PSA升高的患者或早或晚都需进行前列腺穿刺活检术。诚然,PSA指标的普及应用,对前列腺癌早期诊断和密切随访有重要意义,也使得前列腺 Since 1984, the clinical practice has been to rely mainly on PSA tests to screen patients for prostate cancer and to follow up the treatment. Because the diagnosis of prostate cancer relies on pathological examination, a retrospective study found that the vast majority of patients with elevated PSA are required for prostate biopsy sooner or later. Admittedly, the popularization and application of the PSA index is of great significance to the early diagnosis and close follow-up of prostate cancer, and also makes the prostate