Using factorization viewpoint of differential operator, this paper discusses how ti transform a nonlinear evolution equation to infinite-dimensional Hamiltonian linear canonical formulation. It proves a sufficient condition of canonical factorization of operator, and provides a kind of mechanical algebraic method to achieve canonical ’(δ)/(δ)x’-type expression, correspondingly. Then three examples are given, which show the application of the obtained algorithm. Thus a novel idea for inverse problem can be derived fegibly.