论文部分内容阅读
２型糖尿病是以胰岛β细胞胰岛素（Ｉｎｓ）分泌缺陷及Ｉｎｓ抵抗为特征，但其Ｉｎｓ分泌异常的确切机理尚未完全阐明。β细胞跨膜及细胞内信号传导障碍被认为与Ｉｎｓ分泌减低有关。Ｃａ《钙调素（ＣａＭ）系统的发现，为研究Ｉｎｓ分泌机制开辟了新的途径。许多研究表明，
Type 2 diabetes is characterized by insulin secretion deficiency and Ins resistance in pancreatic β cells, but the exact mechanism of its abnormal Ins secretion has not yet been fully elucidated. β-cell transmembrane and intracellular signaling disorders are thought to be associated with decreased Ins secretion. The discovery of Ca-Ca (calmodulin) system opens up new avenues for the study of Ins secretion mechanism. Many studies show that,