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目的了解武汉市新洲区15~16岁高中生人群HBsAg携带情况,评价乙肝疫苗免疫接种的效果。方法通过2005~2008年每年全区高一新生(15~16岁)入学体检,进行血清HBsAg和HBsAb检测。结果2005~2008年新洲区高一新生血清HBsAg阳性率分别为7.23%、6.78%、6.52%、5.88%,HBsAb阳性率分别为31.64%、28.79%、45.61%、39.24%。结论新洲区15~16岁高中生人群HBsAg携带率在逐年下降,仍为中度流行,需要继续加强从儿童期开始的乙肝疫苗免疫接种。
Objective To understand the HBsAg carriers of high school students aged 15-16 years in Xinzhou District of Wuhan City and evaluate the effect of hepatitis B vaccine immunization. Methods The high school freshmen aged 15-16 years from 2005 to 2008 were enrolled in the study, and serum HBsAg and HBsAb were detected. Results The positive rates of HBsAg in HBsAb of high freshmen from 2005 to 2008 were 7.23%, 6.78%, 6.52% and 5.88%, respectively. The positive rates of HBsAb were 31.64%, 28.79%, 45.61% and 39.24%, respectively. Conclusion The HBsAg carrier rate among high school students aged 15-16 years in Xinzhou District is decreasing year by year, and it is still moderate. It is necessary to continue strengthening the immunization of hepatitis B vaccine from childhood.