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本文共收集从1966年1月到1977年12月43例已断经妇女长期服用求偶素后的宫内膜标本,并与同时期某医院妇产科门诊所见到的512例妇女经活检、刮宫或子宫切除获取的宫内膜标本作为对照比较。所有标本均以同样方法处理并经同一病理学家观察。服药组43例,平均年龄55岁(从44～76)。服用合成求偶素Pzemarin。10例每日服0.625毫克,余者每日服1.25毫克,均连用20天,停药7天,不附加黄体酮类药物。服药期间短者半年,长者20年。中位期6～10年,平均期7年8个月。治疗期间的长短与患者年龄有显著关系(r=0.6;P<0.05)。对照
This article collected from January 1966 to December 1977 in 43 cases of women who have been taken after long-term use of ubiquitin endometrial specimens, and with the same period, a hospital obstetrics and gynecology clinic saw 512 women by biopsy, Endometrial specimens obtained by curettage or hysterectomy were compared as controls. All specimens were treated in the same manner and observed by the same pathologist. The medication group of 43 patients, mean age 55 years (from 44 to 76). Take synthetic zeatin Pzemarin. 10 cases daily serving 0.625 mg, 1.25 mg per day for the rest, were used for 20 days, withdrawal for 7 days, no additional progesterone drugs. Short period of six months during the medication, the elderly 20 years. The median period of 6 to 10 years, an average of 7 years and 8 months. The duration of treatment was significantly associated with patient age (r = 0.6; P <0.05). Control