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目的探讨治疗性服用叶酸及多种维生素对缓解胎儿脑室扩张的效果。方法采取便利抽样的方法选取15例B超首次确诊为单纯性脑室扩张的孕妇,治疗性给予叶酸5 mg(1次/d)并配合多种维生素(2次/d)连续服用20 d后复查B超,并比较治疗效果。结果 14例胎儿脑室恢复到正常范围之内,1例由治疗前的11 mm缩小为8 mm,处于临界性脑室扩张,治疗前、后差异有统计学意义(P<0.01)。结论治疗性服用叶酸和多种维生素可以缓解胎儿脑室扩张的进一步发展,有效地预防胎儿中枢神经系统的畸形如脑积水等。
Objective To investigate the therapeutic effect of folic acid and multivitamins on relieving fetal ventricular dilatation. Methods A total of 15 pregnant women with B-ultrasonography diagnosed as simple ventricular dilatation were selected according to the convenience sampling method. The therapeutic effect was folic acid 5 mg (1 time / d) and multivitamin (2 times / d) for 20 days. B super, and compare the treatment effect. Results Fourteen cases of fetal ventricle recovered within the normal range, 1 case was reduced from 11 mm before treatment to 8 mm, and was in critical ventricular dilatation. The difference was statistically significant before and after treatment (P <0.01). Conclusion Therapeutic use of folic acid and multivitamins can relieve the further development of fetal ventricular dilatation and effectively prevent fetal central nervous system deformities such as hydrocephalus.