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使用葡萄糖透析液进行腹膜透析透是治疗终末期肾脏病的有效措施之一。但近年来大量临床研究发现,透析液中葡萄糖对腹膜的结构和功能有重要影响,导致腹膜纤维化,超滤失败,最终放弃腹膜透析。了解透析液中葡萄糖对腹膜的影响及潜在的治疗策略具有十分重要的意义。
Peritoneal dialysis using glucose dialysate is one of the effective measures for the treatment of end-stage renal disease. However, in recent years, a large number of clinical studies have found that the dialysate glucose on the structure and function of the peritoneal membrane have an important impact, leading to peritoneal fibrosis, ultrafiltration failed to eventually give up peritoneal dialysis. It is of great importance to understand the effects of glucose in the dialysis fluid on the peritoneum and potential therapeutic strategies.