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应用荧光偏振技术测定缺血鼠脑线粒体膜流动性。实验结果表明川芎嗪能升高缺血脑线粒体膜的流动性。提示川芎嗪治疗脑梗塞有效,可能与纠正脑梗塞患者脑线粒体膜的分子缺陷,增加脑线粒体膜的流动性有关。
The fluorescence polarization technique was used to determine the cerebral mitochondrial membrane fluidity in ischemic rats. The experimental results show that tetramethylpyrazine can increase the fluidity of ischemic brain mitochondrial membrane. It is suggested that the treatment of cerebral infarction with ligustrazine is effective, which may be related to correcting the molecular defects of brain mitochondrial membrane in patients with cerebral infarction and increasing the fluidity of brain mitochondrial membrane.