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目的分析老年亚临床甲状腺功能亢进症(甲亢)患者采用小剂量他巴唑治疗的临床疗效。方法 100例老年亚临床甲亢患者随机分为对照组和观察组,每组50例。对照组不给予药物治疗,观察组则给予小剂量他巴唑治疗。评估两组治疗效果,统计药物相关不良反应。结果观察组患者治疗总有效率为96.0%,较对照组的70.0%明显更高(P<0.05)。两组患者均未发生明显的药物不良反应。结论在老年亚临床甲亢疾病用药方案中,小剂量应用他巴唑效果满意,可有效改善患者心脏症状,促进患者恢复,安全性高,值得临床予以推广使用。
Objective To analyze the clinical efficacy of metoprolol in elderly patients with subclinical hyperthyroidism (hyperthyroidism). Methods 100 cases of elderly patients with subclinical hyperthyroidism were randomly divided into control group and observation group, 50 cases in each group. The control group was not given drug treatment, the observation group was given a small dose of methimazole treatment. The therapeutic effects of two groups were evaluated, and drug-related adverse reactions were counted. Results The total effective rate of observation group was 96.0%, which was significantly higher than 70.0% of control group (P <0.05). No significant adverse drug reactions occurred in both groups. Conclusions In the scheme of sub-clinical hyperthyroidism in elderly patients, the low dose of metoprolol is satisfactory, which can effectively improve the cardiac symptoms and promote the recovery of patients with high safety. It is worth to be used clinically.