59只兔随机分为对照、氟组、低铝氟组和高铝氟组。经14周亚慢性毒性实验,发现氟和铝在吸收、蓄积及排泄中均产生相互作用,并对Fe、Ca、P等元素产生影响。对照组骨灰铝为43.11ppm,氟组为83.13ppm,低铝氟组为52.45ppm,高铝氟组为32.33ppm。表明氟能促进饲料中本底铝在骨中蓄积,硫酸铝能拮抗这种作用。作者认为铝在氟中毒骨骼病变中有重要作用。 59 rabbits were randomly divided into control, fluoride group, low aluminum fluoride group and high aluminum fluoride group. After 14 weeks of sub-chronic toxicity test, we found that fluoride and aluminum have interaction in the absorption, accumulation and excretion, and have an impact on Fe, Ca, P and other elements. In the control group, aluminum was 43.11 ppm, fluorine group 83.13 ppm, low aluminum fluoride group 52.45 ppm, and high aluminum fluoride group 32.33 ppm. This shows that fluoride can promote the accumulation of background aluminum in the bone in the feed, and aluminum sulfate can antagonize this effect. The authors believe that aluminum plays an important role in the fluorosis of skeletal lesions.