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服苯妥英钠病人中的一半左右,引起牙龈纤维母细胞增殖、组织过长和牙龈增生。本文回顾了近年由苯妥英钠治疗与牙龈增生有关的临床和基础研究。近年研究证明某些因素,可能是增生的致病原因。苯妥英钠引起的牙龈增生常见于前牙的唇侧,开始龈边缘变厚,继而延及牙间乳头。病变的发展除牙龈充满牙间隙外,且不同程度地覆盖牙冠。最初,增生组织
Serving about half of phenytoin sodium patients, causing gingival fibroblasts proliferation, tissue length and gingival hyperplasia. This article reviews the clinical and basic research on the treatment of gingival hyperplasia by phenytoin sodium in recent years. Recent studies have shown that certain factors may be the cause of hyperplasia. Phenytoin-induced gingival hyperplasia is common in the labial side of the anterior teeth and begins to thicken at the gingival margin, which in turn extends to the interdental nipple. Lesions in addition to the development of gums filled with tooth space, and to varying degrees, covering the crown. Initially, hyperplasia tissue