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白细胞介素(Interleukin, IL)是一组参与淋巴细胞分化诱导和免疫调节作用的白细胞生长因子或淋巴因子。自1979年第二届国际淋巴因子专题会议把这类生长因子命名为白细胞介素以来,该领域的研究十分活跃,先后发现了15种白细胞介素(IL-1～15),其特性与功能已被遂渐阐明。其中白细胞介素-2(IL-2)是调节免疫功能最主要的淋巴因子之—;它是由T细胞产生,由133个氨基酸组成的糖蛋白,分子量约15000。在基础研究与临床上测定白细胞介素-2的含量是研究其体内代谢动力学及诊断与人免疫系统相关疾病的重要辅助指标。通过测定人外周血、尿液或人激活淋巴细胞悬浮培养液中的白细胞介素-2水平,可以作为对艾滋病、肿瘤,心血管病、何金氏病、肝炎、肝硬化、红斑狼疮、麻风病等疾病诊断、预后及观察疗效的有效方法,同时也可用于器官移植后有无排异反应的早期诊断。白细胞介素-2水平的测定有生物法、放射免疫法(RIA)、酶联免疫吸附法(ELISA)等,其中以放
Interleukin (IL) is a group of leukocyte growth factor or lymphokine involved in lymphocyte differentiation induction and immune regulation. Since the 1979 International Symposium on Lymphokines has named this type of growth factor as interleukin, research in this area is very active and 15 types of interleukin (IL-1 ~ 15) have been found, their characteristics and functions Has been gradually clarified. Interleukin-2 (IL-2) is the most important lymphokine that regulates immune function - it is a glycoprotein of 133 amino acids produced by T cells and has a molecular weight of about 15,000. Determining interleukin-2 levels in both basic and clinical settings is an important adjunct to studying its in vivo pharmacokinetics and diagnosing diseases associated with the human immune system. By measuring interleukin-2 levels in human peripheral blood, urine, or human activated lymphocyte suspension cultures, it can be used as a marker of AIDS, cancer, cardiovascular disease, ejinkh’s disease, hepatitis, cirrhosis, lupus, Disease and other diseases diagnosis, prognosis and effective observation of the effective method, but also can be used for organ rejection or rejection after the early diagnosis. Interleukin-2 levels are measured by biological assay, radioimmunoassay (RIA), enzyme linked immunosorbent assay (ELISA)