目的评价大剂量尿激酶合并舒血宁治疗发病6小时内急性脑梗死疗效、安全性。方法选择106例病例,分为治疗组56例,对照组50例,对比观察疗效。结果治疗组有效41例(治愈30例,显效11例),颅内出血6例,无效15例,总有效率71.4%,对照组有效24例,无效26例,总有效率48%。结论尿激酶溶栓效果好,相对安全。 Objective To evaluate the efficacy and safety of high-dose urokinase combined with Shuxuening in the treatment of acute cerebral infarction within 6 hours of onset. Methods 106 cases were selected and divided into treatment group (56 cases) and control group (50 cases). The curative effect was observed and compared. Results In the treatment group, 41 cases were effective (30 cases cured and 11 cases markedly effective), 6 cases were intracranial hemorrhage, 15 cases were ineffective and the total effective rate was 71.4%. In the control group, 24 cases were effective and 26 cases were ineffective. The total effective rate was 48%. Conclusion Urokinase thrombolytic effect is good, relatively safe.