正常角结膜上皮细胞为非角化鳞状上皮,其中杯状细胞能产生粘液,参与泪膜的组成。角结膜上皮非角化并产生粘液的特性,对于维持眼球表面组织的完整性至关重要。分泌性或非分泌性的非角化上皮细胞转变成角化的上皮细胞的病理过程称为鳞状上皮化生。许多作者的研究结果表明,这种病理变化存在于许多眼球表面疾患之中,而在临床上处理这类疾患时,对病变程度的精确估计又是十分重 Normal angle conjunctival epithelial cells are non-keratinized squamous epithelium, in which goblet cells can produce mucus, involved in the composition of the tear film. Non-keratinized keratoconjunctival mucilage and the characteristics of the organization to maintain the integrity of the surface of the eye is essential. The pathological process by which secreted or non-secreted non-keratinized epithelial cells transform into keratinized epithelial cells is called squamous metaplasia. Many authors’ findings suggest that this pathological change is present in many ocular surface disorders and that the precise estimation of the extent of the disease is very heavy when dealing with such disorders clinically