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不同程度的2－型糖尿病患者约占世界人口的5％。这种病的一个显著特征是胰腺b－细胞不能对胰岛素需求的增加做出响应。b－细胞缺陷的分子基础不很清楚，影响了对正确治疗方法的研究。纤维原细胞生长因子FGF信号作用与许多器官的发育有关，其中也包括胰脏。Nature杂志2000年
Different degrees of type 2 diabetes account for about 5% of the world’s population. A notable feature of this disease is that pancreatic b-cells do not respond to the increased demand for insulin. The molecular basis of b-cell defects is poorly understood and affects the study of the correct treatment. Fibroblast growth factor FGF signaling role and the development of many organs, including the pancreas. Nature Magazine 2000