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甲状腺功能减退时(简称甲减),患者血脂的变化,已广泛引起注意,即使在亚临床甲减状态,脂质代谢的变化也是明显的。本文旨在探讨甲减患者替代治疗前后血脂变化的特征,进一步认识甲状腺与血脂代谢的关系。 1 临床资料 选取门诊或住院的甲状腺功能减退症患者26例,男6例,女20例,年龄最大58岁,最小23岁,平均年龄43.7岁。诊断依据为典型症状(乏力、怕冷、心动过缓、皮肤干燥、思维迟钝等),血生化检查异常(TT_3、TT_4降低,TSH增高)。其中,桥本氏甲状腺炎13例,甲状腺手术后甲减5例,~(131)Ⅰ放射治疗后甲减7例,特发性甲减1例。无肾病、肾上腺疾病、糖尿病及服用降脂药物和糖皮质激素史。选25例
Hypothyroidism (hypothyroidism), changes in patients with blood lipids, has attracted wide attention, even in subclinical hypothyroidism, changes in lipid metabolism is also obvious. This article aims to explore the hypothyroidism patients before and after treatment of blood lipid changes in the characteristics of thyroid and lipid metabolism to further understand the relationship. 1 clinical data selected outpatient or hospitalized patients with hypothyroidism in 26 cases, 6 males and 20 females, the oldest 58 years old, minimum 23 years old, mean age 43.7 years old. Diagnosis based on typical symptoms (fatigue, cold, bradycardia, dry skin, slow thinking, etc.), abnormal blood biochemical tests (TT_3, TT_4 decreased, TSH increased). Among them, 13 cases were Hashimoto’s thyroiditis, 5 cases were hypothyroidism after thyroid surgery, 7 cases were hypothyroidism after ~ (131) Ⅰ radiotherapy, and 1 case was idiopathic hypothyroidism. No kidney disease, adrenal disease, diabetes and taking lipid-lowering drugs and glucocorticoid history. Select 25 cases