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[目的]探讨中西医结合治疗老年消化性溃疡的临床疗效及安全性。[方法]将2008年1月至2011年1月在我科接受治疗的130例老年消化性溃疡患者随机分为治疗组和对照组各65例,对照组予以奥美拉唑为主的三联疗法治疗,治疗组在对照组的基础上给予自制中药治疗,观察两组患者临床疗效、Hp清除率、复发率及不良反应情况。[结果]治疗组总有效率为92.31%,明显高于对照组的75.38%(P<0.05);两组Hp清除率比较无显著差异(P>0.05);治疗组患者1年后复发率明显低于对照组(P<0.01),两组不良反应均较轻微,且发生率比较无显著差异(P>0.05)。[结论]中西医结合治疗老年消化性溃疡,具有疗效好、复发率低、不良反应少等诸多优点,可作为目前老年消化性溃疡治疗的一种首选方案。
[Objective] To explore the clinical efficacy and safety of integrated traditional Chinese and western medicine in the treatment of senile peptic ulcer. [Methods] A total of 130 elderly patients with peptic ulcer treated in our department from January 2008 to January 2011 were randomly divided into treatment group (65 cases) and control group (65 cases). The control group was treated with omeprazole-based triple therapy The treatment group and the treatment group were given homemade Chinese medicine on the basis of the control group. The clinical efficacy, Hp clearance rate, recurrence rate and adverse reactions of the two groups were observed. [Results] The total effective rate in the treatment group was 92.31%, which was significantly higher than that in the control group (75.38%, P <0.05). There was no significant difference in the Hp clearance rate between the two groups (P> 0.05) Lower than the control group (P <0.01), two groups of adverse reactions were mild, and the incidence was no significant difference (P> 0.05). [Conclusion] Integrative Chinese and Western medicine treatment of peptic ulcer in the elderly, with good efficacy, low recurrence rate, fewer adverse reactions and many other advantages, can be used as the current treatment of peptic ulcer in elderly patients a preferred option.