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目的观察丹参多酚酸盐联合低分子肝素钠治疗不稳定型心绞痛(UA)的有效性和安全性。方法将100例UA患者随机分成两组,治疗组50例,对照组50例。对照组给予硝酸酯类药物、他汀类药物等常规治疗,治疗组在对照组常规治疗基础上应用低分子肝素钠5000U/次,皮下注射,2次/d,连用7d。丹参多酚酸200mg,加入5%葡萄糖250ml中静脉滴注,1次/d,14d为1个疗程。结果观察治疗组心绞痛症状改善总有效率92%,心电图ST-T改善总有效率82%,均优于对照组。结论丹参多酚酸盐联合低分子肝素治疗UA疗效显著,安全可靠,对心肌缺血有明显保护作用。
Objective To observe the efficacy and safety of Salviae miltiorrhizae polyphenols combined with low molecular weight heparin in the treatment of unstable angina pectoris (UA). Methods One hundred patients with UA were randomly divided into two groups: treatment group (50 cases) and control group (50 cases). The control group was given routine treatment with nitrates and statins. The treatment group was given low molecular heparin sodium 5000U / subcutaneously twice a day for 7 days on the basis of conventional treatment in the control group. Salviae polyphenols 200mg, adding 5% glucose 250ml intravenous infusion, 1 / d, 14d for a course of treatment. Results The total effective rate of angina pectoris in treatment group was 92%, and the total effective rate of ECG ST-T improvement was 82%, both of which were better than that of control group. Conclusion Salviae miltiorrhizae polyphenols combined with low molecular weight heparin treatment of UA significant effect, safe and reliable, a significant protective effect on myocardial ischemia.