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恶性胸积液常见于乳腺癌和肺癌转移者。恶性淋巴瘤、卵巢癌、间皮瘤、肉瘤、生殖道和胃肠道恶性肿瘤也可引起恶性胸积液。一般采用化疗、放疗及反复胸穿抽液并注入硬化剂治疗恶性胸积液和控制复发。四环素是一种用以治疗恶性胸积液毒性最少、最广泛和最容易硬化的药剂。有作者推荐在连续两天或几天内反复多次注入四环素治疗。作者为了解1次注入四环素的效果,进行对照研究。病人和方法患胸积液患者50例。其中原发肿瘤为乳腺癌27例,肺癌9例,妇科肿瘤4例,肾癌1例,食管癌1例,膀胱癌1例,不明来源腺癌3例,肉瘤
Malignant pleural effusion is common in breast cancer and lung cancer metastasis. Malignant lymphoma, ovarian cancer, mesothelioma, sarcoma, reproductive tract, and gastrointestinal cancer can also cause malignant pleural effusion. General chemotherapy, radiotherapy and repeated thoracentesis and injection of sclerosing agent for the treatment of malignant pleural effusion and control of recurrence. Tetracycline is an agent that is used to treat malignant pleural effusion with the least toxicity, the most extensive, and the easiest to harden. It has been recommended by the author that multiple doses of tetracycline be administered repeatedly over two consecutive days or days. To understand the effect of one injection of tetracycline, the authors performed a controlled study. Patients and Methods 50 patients suffering from pleural effusion. The primary tumors included 27 cases of breast cancer, 9 cases of lung cancer, 4 cases of gynecologic tumors, 1 case of renal cancer, 1 case of esophageal cancer, 1 case of bladder cancer, 3 cases of adenocarcinoma of unknown origin, and sarcoma.