论文部分内容阅读
目的:探讨利巴韦林气雾剂局部喷射与静脉滴注治疗手足口病普通病例的疗效。方法:将2013年4月至2013年8月确诊的手足口病普通病例患儿111例按就诊时间依次分为对照组和治疗组,两组均在常规治疗的基础上,对照组给予利巴韦林注射液静脉滴注,治疗组给予利巴韦林气雾剂治疗,观察两组临床疗效和不良反应。结果:治疗组的口腔溃疡与皮疹消退时间明显短于对照组(6.5±1.1d vs 7.4±1.6 d,P<0.05),但两组退热时间无明显差异(1.0±0.4 d vs 1.0±0.6 d,P>0.05)。结论:与利巴韦林静脉滴注相比,利巴韦林气雾剂在治疗手足口病普通病例具有更好的临床效果。
Objective: To investigate the efficacy of ribavirin aerosol local injection and intravenous drip in the treatment of common cases of hand, foot and mouth disease. Methods: A total of 111 children with HFMD diagnosed from April 2013 to August 2013 were divided into control group and treatment group according to visiting time. Both groups were given routine treatment, Weilin injection intravenous infusion, the treatment group was given ribavirin aerosol treatment, the two groups observed clinical efficacy and adverse reactions. Results: The oral ulcer and rash subsided time of the treatment group was significantly shorter than that of the control group (6.5 ± 1.1d vs 7.4 ± 1.6d, P <0.05), but there was no significant difference between the two groups (1.0 ± 0.4d vs. 1.0 ± 0.6 d, P> 0.05). CONCLUSIONS: Ribavirin aerosols have better clinical outcomes in the treatment of common cases of HFMD compared with intravenous ribavirin.