我们通过对尤文肉瘤凋亡指数及相关调控基因ｐ16、ｐ15蛋白的检测,了解其在尤文肉瘤中的表达水平,并初步探讨其临床及生物学意义。1　材料与方法11　临床资料　1990年3月～1997年8月,经临床、Ｘ线、病理确认为尤文肉瘤的患者12例,男9例,女3例,年龄23～46岁。12　方法　标本均采 We detect the expression of p16, p15 protein in Ewing’s sarcoma by detecting the apoptosis index of Ewing’s sarcoma and its related regulatory genes, and discuss its clinical and biological significance. 1 Materials and Methods 11 Clinical data March 1990 ~ August 1997, by clinical, X-ray, pathological confirmed as Ewing sarcoma in 12 patients, 9 males and 3 females, aged 23 to 46 years. 12 method specimens are collected