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乙型肝炎病毒（ＨＢＶ）不是致细胞病变性病毒，重型肝炎的发生一般认为主要是机体对ＨＢＶ过强的免疫应答所致。ＨＢＶ的清除主要依赖ＣＫＤ８＋细胞毒性Ｔ淋巴细胞（ＣＴＬ）对ＨＢｃＡｇ的免疫应答。我们对１１例重型肝炎患者中扩增的ＨＢＶＣ基因序列测序分析，试图阐...
Hepatitis B virus (HBV) is not a cytopathic virus, the incidence of severe hepatitis is generally believed that the body is due to excessive HBV immune response. HBV clearance depends mainly on the immune response of CKD8 + cytotoxic T lymphocytes (CTLs) to HBcAg. We sequenced the sequence of HBVC gene amplified in 11 patients with severe hepatitis, trying to elucidate ...