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冠脉微循环担负着心肌营养的任务。要使心肌营养物质和氧的供应增加,只有改善冠脉循环,增加心肌营养性血流量。根据费克原理,在一定条件下,血流量与心肌对铷(Rb)的摄取量呈正比关系。据此,中国医学科学院药物研究所研究了用~(86)Rb 测量小鼠心肌营养性血流量的方法,并进行了实验研究,认为小鼠心肌对~(86)Rb 摄取能力的大小,反映了心肌营养性血流量的速度。在此基础上,一些学者用放射性核素~(86)Rb 研究了一些药物对小
Coronary microcirculation is responsible for the task of myocardial nutrition. To increase the supply of nutrients and oxygen to the heart muscle, only the coronary circulation is improved and the myocardial nutrient blood flow is increased. According to the Fei Ke principle, under certain conditions, the blood flow is positively correlated with the myocardial uptake of radon (Rb). Based on this, the Institute of Materia Medica, Chinese Academy of Medical Sciences studied the method of measuring myocardial nutrient blood flow in mice with ~(86)Rb, and conducted an experimental study. It was considered that the size of ~(86)Rb uptake by mouse myocardium The rate of myocardial nutrient blood flow. On this basis, some scholars have studied some drugs against radionuclides ~(86)Rb