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儿茶酚胺(CA)调节肾功能,包括肾血流量、肾小球滤过作用、肾小管的离子运转、肾素和红细胞生成素的释放等。 CA经α_1受体收缩肾血管、增加血管阻力、减少血流量,但肾内各部分血管对CA的敏感性有所不同。含去甲肾上腺素(NE)的神经末梢分布于肾、弓状和小叶间动脉,肾小管和近球小体周围血管,以及1/3的出与入球小动脉上。肾内β受体的扩血管作用弱于其它血管床,也小于α受体的作用;但某些部位(如营养肾小管—血管球反馈机制的血管)富有β受体。肾
Catecholamine (CA) regulates renal function, including renal blood flow, glomerular filtration, iontophoresis of the tubules, release of renin and erythropoietin, and more. CA by α_1 receptor contraction of renal blood vessels, increase vascular resistance, reduce blood flow, but the various parts of the renal blood vessels of CA sensitivity is different. Nerve endings containing norepinephrine (NE) are located in the kidneys, arcuate and interlobular arteries, perirenal and proximal perivascular vessels, and 1/3 of the exit and afferent arterioles. The vasodilator effects of intrarenal β receptors are weaker than those of other vascular beds and also less than that of α receptors; however, β receptors are abundant in some sites (eg, the vessels of the nutrient tubule-vaso-glomerular feedback mechanism). kidney