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探讨用恶性肿瘤特异性生长因子(TSGF),糖抗原19-9(CA19-9)与糖抗原242(CA242)联合检测对消化道恶性肿瘤的临床诊断价值。方法 采用酶联免疫测定136例消化道肿瘤及50例正常人血清。结果 以单一指标阳性作为诊断标准,CA242、CA19-9、TSGF对消化道恶性肿瘤的灵敏度分别为41.2%,55.9%,74.3%,准确度分别为57.0%,65.1%,75.8%,三项联合检测诊断灵敏度上升为89.7%,准确度为87.1%(P<0.05)。结论 联合检测血清TSGF、CA19-9与CA242对消化道恶性肿瘤的辅助诊断有较高的临床应用价值。
To investigate the clinical value of combined detection of TSGF, CA19-9 and CA242 in the diagnosis of gastrointestinal malignancies. Methods Enzyme - linked immunosorbent assay was performed on 136 cases of gastrointestinal tumors and 50 cases of normal human serum. Results The sensitivity of CA242, CA19-9 and TSGF to gastrointestinal malignancies was 41.2%, 55.9% and 74.3%, respectively, with the accuracy of 57.0%, 65.1% and 75.8%, respectively. The diagnostic sensitivity increased to 89.7% with an accuracy of 87.1% (P <0.05). Conclusion Combined detection of serum TSGF, CA19-9 and CA242 has high clinical value in the diagnosis of gastrointestinal malignancies.